Celebrex (Celecoxib)

Celebrex Information

Celebrex is a NSAIDs drug (Non-steroidal Anti Inflammatory medicine). As a NSAID drug, Celebrex fights against inflammation, pain or swelling by reducing the amount of substances that cause them.

Celebrex used to reduce inflammation and ease mild to moderate pain for such conditions as arthritis or painful menstrual cycles. Celecoxib may also be used to treat certain other conditions such as familial adenomatous polyposis (FAP). Generic celecoxib capsules are not available.

Most important fact about Zanaflex

Celebrex contain the active ingredient celecoxib, which is a type of medicine known as a non-steroidal anti-inflammatory drug (NSAID).

NSAIDs work by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in producing prostaglandins, in response to injury or certain diseases. These prostaglandins cause pain, swelling and inflammation. Because NSAIDs block the production of these prostaglandins, they are effective at relieving pain and inflammation.

Cyclo-oxygenase does not only produce prostaglandins that cause inflammation. It also produces prostaglandins that have useful roles in the body. There are two different forms of cyclo-oxygenase, COX-1 and COX-2. COX-2 is the form that (among other things) produces prostaglandins that cause inflammation. COX-1 does not produce inflammatory prostaglandins, but does produce others that have useful effects, including some that are involved in maintaining a healthy stomach and intestinal lining.

Traditional NSAIDs, such as ibuprofen or diclofenac, block the action of both COX-1 and COX-2, and this is why they can sometimes cause side effects such as stomach irritation and peptic ulcers. Celecoxib belongs to a new generation of NSAIDs that selectively block the action of COX-2. This means that it stops the production of inflammatory prostaglandins, without stopping the production of prostaglandins that protect the stomach and intestines. It therefore reduces pain and inflammation, but is less likely than traditional NSAIDs to cause side effects on the stomach and intestines (although such side effects are still possible).

Celebrex Indications

Celebrex is usually prescribed to patients who suffer from Stiffness, pain or inflammation which may accompany Osteoarthritis or rheumatoid arthritis. Celebrex helps ease these symptoms while also decreasing the amount of polyps from your body (familial adenomatous polyposis, adenomatous colorectal polyps). Celecoxib is also indicated for patients experiencing acute pain and even menstruation related pains.

Celebrex must be taken in according to your doctor’s recommendations. Therefore, a patient who is following a treatment with Celebrex must take into consideration each and every instruction that their doctor has given them. Every dose of Celebrex should be taken along with a glass of water. A patient who has been prescribed a daily low dosage of the drug may not need to eat food or drink milk prior to the dose’s intake. However, in the case of higher doses, the patient should reinforce his or her stomach with some food or liquids before taking Celebrex, to avoid

What drug(s) may interact with Celebrex ?
•alcohol
•alendronate
•amiodarone
•aspirin
•bosentan
•cidofovir
•cimetidine
•clopidogrel
•cyclosporine
•delavirdine
•drospirenone; ethinyl estradiol (Yasmin®)
•entecavir
•fluconazole
•herbal products that contain feverfew, garlic, ginger, or ginkgo biloba
•imatinib, STI-571
•isoniazid, INH
•ketoconazole (oral products)
•lithium
•medicines for high blood pressure
•methotrexate
•other anti-inflammatory drugs (such as ibuprofen or prednisone)
•pemetrexed
•rifampin
•selective serotonin reuptake inhibitors (SSRI, examples: fluoxetine, fluvoxamine, paroxetine)
•ticlopidine
•warfarin
•water pills (diuretics)